Peptinnovate announces change of name to Immune Regulation, strengthening of the Board and successful fundraise

Peptinnovate Ltd (‘Peptinnovate’ or the ‘Company’, a biotechnology company developing novel immune modulators for immunological and inflammatory diseases, announces that it has changed its corporate name from Peptinnovate to Immune Regulation with immediate effect. The new website for Immune Regulation is www.immuneregulation.com.

Richard Nagle, CEO of Immune Regulation, formerly Peptinnovate, commented:
“Re-branding the Company as Immune Regulation better reflects our expanding clinical pipeline of novel immuno-modulating therapies following Peptinnovate’s acquisition of Immune Regulation Ltd. and its lead molecule, IRL201805 earlier this year.

“IRL201805 is currently in clinical development for rheumatoid arthritis. Along with our other lead drug candidate IRL201104, currently in clinical development for asthma and dermatological indications, we now have two therapeutic development programmes that have successfully completed early stage clinical studies. We are continuing to execute on our vision to develop these first in class immune-modulators in a broad range of immunological and inflammatory diseases.”

Board appointments
Immune Regulation also announces a significant strengthening of its Board of Directors and scientific team with the appointment of Dr Dominik Escher as Non-Executive Director and Vice Chairman, Dr Ben Cons as Non-Executive Investor Director and Dr Roly Foulkes as Chief Scientific Officer (CSO).

Dr Dominik Escher, Ph.D. has significant experience as a successful biotechnology entrepreneur and a leader in therapeutic development in both the start-up and corporate pharmaceutical environments. He was founder and former CEO of ESBATech, whose ophthalmology business was acquired by Alcon, in a deal valued at up to $589m, and later integrated into Novartis. He has held multiple senior positions, including Board member, Vice President, and CEO at several other companies, including Delenex Therapeutics, CDR-Life, and Pureos Bioventures. Dominik obtained his Ph.D. from the University of Zurich. He is also a board member of the Swiss Biotech Association, which he has led as President since 2013.

Dr Ben Cons has more than 30 years’ experience in pharmaceutical R&D & commercialisation in the biotech, pharmaceutical and financing sectors. Ben has 20 years of experience with the NYSE-listed pharmaceutical services company IQVIA and the associated NovaQuest investment fund. He is currently a Special Partner at the private equity fund Vitruvian and a board advisor to Talking Medicines. He is also an investment member of private capital group, 24Haymarket and an investment panel member at Future Care Capital, a charity focusing on future health and social care policy.

Dr Roly Foulkes is an internationally recognised leader in drug discovery and development, with extensive experience in immunology. His latest role was Vice President Immunology Research at UCB where he was also Chair of the Immunology Therapeutic Area Strategy Team, and Head of Immunology Discovery Research. Since 2012, he has advised small and medium sized biopharma companies within the immunology field, to develop competitive therapeutic strategies and bring new innovative molecules to the clinic.

Commenting on the appointments, Prof. Clive Page, Chairman of Immune Regulation said,
“The appointment of these three experienced industry executives will bring valuable insight and resource to our Board and executive team. With their skills in immunology, clinical therapeutic development and strategy we have the expertise to advance our clinical programmes and look forward to the next stage of our progress.”

In the first half of 2018, Immune Regulation successfully closed a funding round, raising £4 million. The round was co-led by founding investor Metellus and new investor 24Haymarket through the issue of equity.

Immune Regulation
Richard Nagle, CEO
+44 (0)7809 525267

Instinctif Partners
Melanie Toyne-Sewell / Rozi Morris
+44 (0)20 7457 2020

About Immune Regulation
Formerly known as Peptinnovate Ltd, Immune Regulation is a drug development company developing ‘first in class’ immune resetting therapies for asthma and other chronic inflammatory diseases. The products under development by Immune Regulation have the potential to significantly advance the control and management of a range of chronic inflammatory diseases, with the potential for immune regulation, disease modification and remission.

About IRL201104
PIN201104, is uniquely safe and efficacious demonstrating immunoregulatory activity in a number of preclinical models. It has successfully completed Phase 1 clinical development and has the potential to be the first Immune Resetting Asthma Drug (IMRAD).

About IRL201805
IRL201805 or ‘1805, has shown promising data following a single dose in a Phase 1/2a human study in patients with rheumatoid arthritis and published in the peer-reviewed journal, Rheumatology. Similar to ‘1104, ‘1805 has shown a safety and side effect profile similar to placebo in this study.

22 November 2018

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David Southwell


In addition to his role as Chairman of Revolo, David Southwell serves on the Board of Directors for Rocket Pharmaceuticals and PTC Therapeutics. David is the former CEO of TScan Therapeutics. Before that, he served as President and CEO of Inotek Pharmaceuticals until its merger with Rocket Pharmaceuticals in 2018. David has held other senior leadership roles and Board of Director positions at companies including Human Genome Sciences, Sepracor, Spero Therapeutics, inVentiv Health, and THL Credit.

Kari Brown, M.D.

Executive Vice President, Clinical Development, Operations and Strategy

Kari Brown, a board-certified allergist and immunologist, brings 10 years of experience in clinical treatment deployment, development and strategy to Revolo. In her various roles, Kari has played an integral part in advancing pipelines across allergy and immunology disease indications.

Femi Oluboyede

Vice President, Technical Operations, CMC

Femi Oluboyede has over 20 years of experience within the bio-pharma industry, with a proven track record of achieving strategic corporate objectives. Through his roles, Femi has excelled in fostering alignment across functional teams, including Process Development, Tech-transfers, cGMP Manufacturing in Biologics, Small molecules, Proteins and Synthetic Peptides. He has succeeded in delivering investigational products and providing support across different phases of clinical trials.

Tunde Otulana, M.D.

Non-Executive Director

Tunde is currently the Chief Medical Officer of Veloxis Pharmaceuticals in North Carolina, USA since August 2020. Prior to Veloxis he was Senior Vice President and Chief Medical Officer at Mallinckrodt Pharmaceuticals. His career, which spans about 30 years in industry, government and academia, includes leadership roles at Boehringer Ingelheim Pharmaceutical Inc. and the US Food and Drug Administration (“FDA”). Tunde is a physician trained in Pulmonary and Critical Care Medicine.

Beth Alley

Vice President, Regulatory Affairs

Beth Alley has over 20 years of experience within the biopharmaceutical industry in regulatory affairs, commercial strategy, and medical writing throughout all phases of drug development. Her primary areas of focus have been in development of biologics for treatment of autoimmune, inflammatory, and infectious diseases.

Glen Giovanetti

Non-Executive Director

Glen Giovanetti has more than 35 years of experience in strategy and operational leadership in the life science industry as well as in financial governance, risk and reporting as EY’s Global Biotechnology Sector Leader and Life Sciences Sector Leader. He currently serves on the Board of Directors of Life Science Cares, Teon Therapeutics and XW Pharma.

Marla S. Persky

Non-Executive Director

Marla S. Persky currently serves as the chief executive officer and president of WOMN LLC. She has more than 25 years of international senior business and legal experience in the pharmaceutical industry having held numerous business and legal positions at Boehringer Ingelheim and Baxter International. She currently serves on the Boards of Directors of Xeris Pharmaceuticals, YGEIA Consulting Group, Primary Stages, World Neighbors and A Better Chance in Ridgefield.

Dora Rau

Senior Vice President, Quality

Dora Rau brings 25 years of experience in development and commercial operations for drugs, biologics, devices and combination products to the team. She has held numerous executive-level quality positions, with expertise in building quality systems and in leading teams to attain successful regulatory authority inspection outcomes and product approvals.

Jonathan Gold

Chief Financial Officer

Over the last 25 years, Jonathan Gold has been an institutional venture capitalist, a public fund manager, a founder, an operating executive, and a board member for companies across sectors including life sciences. In those roles, he was active in the development, financing and mergers and acquisitions for numerous public and private companies.

Team Members

Michael Albisser

Non-Executive Director​

Michael is a partner of Metellus, a Zurich and London-based venture capital firm investing in technology and life sciences with ground-breaking potential. Having more than 25 years of experience in the finance area he is responsible for finance, tax, and deal structures. He serves on the board of various venture-backed companies.

Dr. Isaac Cheng, m.d.

Non-Executive Director

Dr. Isaac Cheng is currently an investment professional at Morningside, a venture capital and private equity institution based in Boston USA, and Shanghai China. Dr. Cheng focuses primarily on biopharmaceutical and healthcare investments. He has served on numerous public and private company boards.

Peter Greenleaf

Non-Executive Director

Peter Greenleaf currently serves as the chief executive officer (CEO) and member of the Board of Directors of Aurinia, (NASDAQ: AUPH / TSX: AUP), an autoimmune therapeutics company. He has held several other CEO and chairman roles. He is also currently a member of the Board of Directors of Antares Pharmaceuticals, Inc. (NASDAQ: ATRS) and Chairman of the Board of Directors of Biodelivery Sciences International, Inc. (NASDAQ: BDSI).

Marylyn Rigby

SVP of Marketing and Investor Relations

Marylyn Rigby is an experienced pharmaceutical, biotech, and drug delivery professional. In addition to her expertise in marketing, public and investor relations, she has a successful track record with business development, licensing, public and private equity financing, strategy and other key corporate functions.

Nancy Vinh

SVP of Clinical Operations

Nancy Vinh brings over 20 years of experience in managing early and late phase, international clinical trials for drugs, biologics, cell therapy and combination products across a wide range of therapeutic areas to the team. She has served as head of clinical operations and led registrational and label expansion trials execution.

Team Members

Dr. Clare Burgess

Chief Development Officer

Dr. Clare Burgess has 24 years of experience in clinical drug development as a pharmacologist and has worked across a wide range of therapeutic areas within the pharmaceutical industry. She has held multiple leadership roles and has led multidisciplinary teams across the world.

Jeff Myers, m.d., ph.d

Chief Medical Officer

Jeff Myers, M.D., Ph.D., has 20 years of experience in medical affairs, regulatory and clinical development within the biopharmaceutical industry, with focuses on cardiovascular, pulmonary, oncology, and inflammatory diseases.

Before entering the industry, he practiced as a congenital cardiac surgeon and served as the chief of pediatric cardiac surgery at Massachusetts General Hospital and as Associate Professor of Surgery at Harvard Medical School.

Team Members

Dr. Roly Foulkes

Chief Scientific Officer

A true drug discoverer, Dr. Roly Foulkes has 25 years of experience building and delivering innovative therapeutic portfolios within the immunology and inflammatory disease space. He has a strong record advising small and medium sized immunology biopharma companies in developing competitive therapeutic strategies and bringing new innovative molecules to the clinic.

Team Members

Jones w (woody) Bryan, ph.d.

President & Chief Executive Officer

Jones (Woody) Bryan, Ph.D., brings almost 30 years of experience in the healthcare industry to the team, having led successful business development operations in both private and public pharma and biotech companies.

Team Members

Jonathan Rigby, mba

Group Chief Executive Officer

As employee #1 of Revolo Biotherapeutics in the US, Jonathan Rigby has led the company through substantial and rapid growth. He brings three decades of experience creating value and opportunities for companies in the pharmaceutical, biotech and drug delivery technology industry.

Team Members